8,836 Reviews

L-ARGININE

L-ARGININE

BUNDLE & SAVE

View full details

Learn more aboutL-Arginine

check_box

1 .What it is

Sustained Release Arginine is a dietary supplement that provides a sustained-released form of L-Arginine, an amino acid that is important for maintaining cardiovascular health and supporting various metabolic functions in the body.*

check_box

2. Who it's for

This product is perfect for adults interested in promoting their cardiovascular health, maintaining healthy blood pressure levels already within the normal range, or enhancing overall wellness and athletic performance.

check_box

3. How to take it

As a dietary supplement for adults, take three (3) tablets twice daily, preferably with meals, or as directed by your healthcare practitioner. It is normal for this product to have a distinctive botanical aroma.

check_box

4. Bonus benefits

In addition to its primary cardiovascular benefits, L-Arginine may also support immune health, help in detoxification, aid in protein synthesis, and play a role in hormone regulation and male fertility.*

check_box

5. If you really like science

Sustained Release Arginine contains L-Arginine, a semi-essential amino acid known for its involvement in multiple metabolic pathways, particularly its role as a precursor to nitric oxide (NO), a key signaling molecule in the cardiovascular system. Adequate levels of L-Arginine are necessary for the production of NO, which promotes vasodilation and helps maintain blood flow and vascular tone (1). The sustained-release formulation is designed to release L-Arginine gradually over 4 to 6 hours, helping to ensure optimal absorption and plasma levels, which is crucial during periods of metabolic stress. Clinical studies have demonstrated that L-Arginine supplementation may support the maintenance of blood pressure in the normal range and promote healthy endothelial function, which supports overall cardiovascular health (2). Furthermore, L-Arginine is also critical in protein synthesis, immune modulation, and hormone regulation, making it an essential component for overall health (3).*

check_box

6. Inactive Ingredients

Calcium phosphate, vegetable wax (rice bran and/or carnauba wax, stearic acid (vegetable), magnesium stearate (vegetable), silica.

check_box

7. Precautions

Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking any medications, or are nursing or pregnant. As with all dietary supplements, keep out of reach of children.

check_box

8. Product Quality Control Tests Performed

L-Arginine SR is manufactured in the United States (Oregon) in a state-of-the-art, FDA-registered facility that meets or exceeds current Good Manufacturing Practices (cGMP). Quality control tests are performed at every stage of the manufacturing process from rigorous raw material testing to finished product testing.

check_box

9. References

  1. Morris SM Jr. Arginine metabolism revisited. J Nutr. 2016;146(12):2579S-2586S. https://pubmed.ncbi.nlm.nih.gov/27934648/.
  2. Miller AL. The effects of sustained-release L-arginine formulation on blood pressure and vascular compliance in 29 healthy individuals.  Altern Med Rev. 2006;11(1):23-9. https://pubmed.ncbi.nlm.nih.gov/16597191/.
  3. Oyovwi MO, Atere AD. Exploring the medicinal significance of l-Arginine mediated nitric oxide in preventing health disorders. Eur J Med Chem Reports. 2024;12:100175. https://doi.org/10.1016/j.ejmcr.2024.100175

Trustpilot reviews

Excellent 4.8 / 5

  • Staying Healthy

    I have been using Endurance supplements for over 5 years now, L-Arginine helps me along with daily aerobic exercise to maintain the circulatory system conduit. Retired, no distractions, adding healthy years to happily everafter ; ).

    Carol Cooper

  • You Get What You Pay For

    Tried the GNC 1,000 mg pill and after a few days have gone back to Endurance. The cheaper alternative was not buffered and/or sustained release and I did not tolerate it well.

    Erich Steinhauser

  • Great product!

    I’ve been using Endurance Products SR L-Arginine for years. It is a top-of-the- line supplement. If I could make one request … would you be able to increase the mg. in each tablet to 500 or (better yet) 1,000 mg. Other manufacturers do this, so is it something you’d consider?

    I’m all for using the smallest number of tabs or caps to achieve the same effect!

    Paul Anson

  • L-Argenine

    Been using it for years. Really does the job on relaxing the arteries. High BB? You’ll win by combining this product with routine exercise, proper diet and a good attitude!

    Larry Parrish

  • Thank you

    I have received the product, I will not be able to review just yet I will wait till I have been using for at least 30 days, for results.

    John Montero

  • Improves BP and other things as well

    This product really works. Helps lower BP and an extra added benefit that my wife likes as well.

    daryl blevins

    Providing high-quality sustained-release supplements since 1978

    • Only What You Need

      No salt, sugar, starch, artificial colors or flavorings, or preservatives

    • Easy to Swallow

      The shape and size of our tablets make it easy for you to take your supplements

    • Backed by Science

      Backed by a portfolio of clinical research

      • Immediate ReleaseChewable, Softgel, Tablet

        • Quickly dissolves for rapid onset of action
        • Ideal for absorption of fat-soluble nutrients
        • Ideal for nutrients intended to work in the digestive tract
        • Well tolerated by sensitive people

      • Time ReleaseExtended or Sustained Release Delivery

        • Offers convenience with the fewest number of tablets and daily
        • Easy-to-swallow tablets without unnecessary coating ingredients
        • Promotes comfort, including digestive comfort and reduced niacin flush
        • Superior tablet stability with our vegetable wax matrix
        • Helps ensure optimal therapeutic effect
        • No unexpected dose dumping with slow, steady nutrient release